paxilline Facts Sheet
(main)
This mini website about
paxilline was prepared by a student of BioInformatics, the Open University.
alternate names: paxilline
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source |
Potent
inhibitor of Ca activated K(maxi K) channel. Potent Neurotoxin
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CalBioChem |
A tremorgenic indole alkaloid that blocks high conductance
Ca2+-activated K+-channels. Enhances binding of charybdotoxin to
maxi-K+-channels. |
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source |
... This compound is a proposed intermediate in the
biosynthesis of several other indole-diterpenes including lolitrem B
produced by Epichloe grass endophytes... |
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source |
... genetic aspects of Paxilline biosynthesis ... |
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biochemicals . net |
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10
mg= $100.00, 50 mg = $450.00 |
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AG Scientific |
10 mg =
$100.00 , 50 mg = $450.00 |
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the 10 selected
paxilline abstracts
| 1 |
The mechanism of inhibition of the sarco/endoplasmic
reticulum Ca2+ ATPase by paxilline. |
| 2 |
The mycotoxin paxilline inhibits the cerebellar
inositol 1,4, 5-trisphosphate receptor. |
| 3 |
Effects of paxilline on K+ channels in rat mesenteric
arterial cells. |
| 4 |
Tremorgenic mycotoxins paxilline, penitrem and
lolitrem B, the non-tremorgenic 31-epilolitrem B and electromyographic
activity of the reticulum and rumen of sheep. |
| 5 |
Paxilline-negative mutants of Penicillium paxilli
generated by heterologous and homologous plasmid integration. |
| 6 |
Effect of the mycotoxins penitrem, paxilline and
lolitrem B on the electromyographic activity of skeletal and
gastrointestinal smooth muscle of sheep. |
| 7 |
Effects of the K+ channel blockers paspalitrem-C and
paxilline on mammalian smooth muscle. |
| 8 |
Paxilline inhibition of the alpha-subunit of the
high-conductance calcium-activated potassium channel. |
| 9 |
Modulation of the Ca(2+)-dependent K+ channel, hslo,
by the substituted diphenylurea NS 1608, paxilline and internal Ca2+. |
| 10 |
Oxidative transformation of paxilline in sheep bile. |
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